This study aimed to investigate the impact of caloric restriction (CR) on cognitive function in aged C57BL/6 mice after surgery, as well as the underlying mechanisms.Forty 14-month-old male C57BL/6 mice were randomly assigned to the ad libitum (AL, n = 20) Face Mirrors group and the CR (n = 20) group.After feeding for 12 weeks, they were subdivided

In object segmentation, the existence of hard-classified-pixels limits the segmentation performance.Focusing on these hard pixels through assigning different weights to pixel loss can guide the learning of segmentation model effectively.Existing loss weight assignment methods perceive pixels hardness by current predicted information, pay less atten

Background People with mental illness have higher rates of smoking than the general population and are at greater risk of smoking-related death and disability.In smokers from the general population, electronic cigarettes (e-cigarettes) have been shown to have a similar effect on quit rates as nicotine replacement therapy, but little is known about

The role of multiparametric MRI (mpMRI) in the detection of prostate cancer is well-established.Based on the limited role of dynamic contrast enhancement (DCE) in PI-RADS v2.1, the risk of potential side effects, and the increased cost and time, there has been an increase in studies advocating for the omission of DCE from MRI assessments.Per PI-RAD

Traditionally, the structure of higher-order data in genotype-by-environment interaction requires simplification to use bilinear reduction models.Flexible multiway reduction models have been claimed to be more informative, as they allow exploration of individual trends and account for the covariance among data modes.In complex latent traits, such P